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材料研究学报  2008, Vol. 22 Issue (5): 495-499    
  论文 本期目录 | 过刊浏览 |
可降解纯铁薄膜的制备和血液相容性
朱生发;徐莉;李贵才;石志峰;孙鸿;黄楠
西南交通大学材料先进技术教育部重点实验室;中国工程物理研究院
The preparation and blood compatibility of pure iron thin film using filter cathode vacuum arc
Sheng-Fa ZHU;;;;;
西南交通大学材料先进技术教育部重点实验室;中国工程物理研究院
引用本文:

朱生发; 徐莉; 李贵才; 石志峰; 孙鸿; 黄楠 . 可降解纯铁薄膜的制备和血液相容性[J]. 材料研究学报, 2008, 22(5): 495-499.
, , , , , . The preparation and blood compatibility of pure iron thin film using filter cathode vacuum arc[J]. Chin J Mater Res, 2008, 22(5): 495-499.

全文: PDF(700 KB)  
摘要: 用磁过滤阴极真空弧源法在单晶硅基片上制备纯铁薄膜,分析了薄膜表面的组成、元素价态和薄膜的物相结构,研究了薄膜的腐蚀降解行为和抗凝血性能. 结果表明:具有纳米晶粒的纯铁薄膜其腐蚀速率低于普通晶粒的纯铁,在纯铁薄膜表面粘附的血小板数量少于316L不锈钢, 且激活和团聚比较轻微,增生的伪足数量比较少;纯铁薄膜表面对血浆中的凝血因子激活比较轻微,具有较好的抗腐蚀性和血液相容性.
关键词 金属材料纯铁薄膜磁过滤阴极弧源    
Abstract:Iron thin film were deposited on silicon substrate using filter cathode vacuum arc. Composition and valence studies were carried out by X-ray photoelectron spectroscopy (XPS); Glancing angle X-ray diffraction (GAXRD) was employed to examine the phase structure. In vitro blood compatibility tests, including platelet adherent, prothrombin time(PT) and thrombin time(TT), were used to evaluate the antithrombogenic properties. Scanning electron microscopy (SEM) and optical microscopy were employed to evaluate the surface morphology of the blood platelets on the films. The results have shown that the number of adherent platelets, the aggregation and pseudopodium were reduced compared to that observed on the 316L stainless steel. The PT and TT for iron thin films are almost the same as for the original plasma, which indicates that the tendency for activating blood coagulation factors is very slight.
Key wordsFilter cathode vacuum arc    iron thin film    blood compatibility
收稿日期: 2007-10-16     
ZTFLH:  TB43.R318  
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