Please wait a minute...
材料研究学报  2012, Vol. 26 Issue (1): 85-90    
  研究论文 本期目录 | 过刊浏览 |
聚丙烯酸类水凝胶的制备及其在碱性溶液中的pH敏感性
杨玉霞, 杨怀玉
中国科学院金属研究所金属腐蚀与防护国家重点实验室 沈阳 110016
Preparation of Polyacrylic Acid Type Hydrogel and Its pH Sensitive Behavior in Alkaline Solution
YANG Yuxia, YANG Huaiyu
State Key Laboratory for Corrosion and Protection, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016
引用本文:

杨玉霞 杨怀玉. 聚丙烯酸类水凝胶的制备及其在碱性溶液中的pH敏感性[J]. 材料研究学报, 2012, 26(1): 85-90.
, . Preparation of Polyacrylic Acid Type Hydrogel and Its pH Sensitive Behavior in Alkaline Solution[J]. Chin J Mater Res, 2012, 26(1): 85-90.

全文: PDF(969 KB)  
摘要: 以(NH4)2S2O8和NaHSO3为氧化--还原引发剂、N, N'--亚甲基双丙烯酰胺(MBA)为交联剂, 采用自由基水溶液聚合方法, 分别合成了聚丙烯酸(PAAc)、聚丙烯酰胺(PAAm)和系列丙烯酸(AAc)质量分数(fAAc)不同的聚(丙烯酸--co--丙烯酰胺)(P(AAc--co--AAm))水凝胶。进而分别对其在碱性缓冲溶液和NaOH溶液中的pH敏感行为进行了探讨。结果表明, PAAc和P(AAc--co--AAm)凝胶在2种溶液中均具有优良的pH响应行为, 且在NaOH溶液中的溶胀比大于缓冲溶液中; 而PAAm凝胶仅在NaOH溶液中具有pH敏感性。2种溶液中, 随fAAc的增加, P(AAc--co--AAm)凝胶的平衡溶胀比(ESR)增大; 但在缓冲溶液中, 当fAAc≧20%时, P(AAc--co--AAm) 凝胶的溶胀行为与PAAc相似, 而当fAAc<20%时, 其溶胀则同时表现出PAAc和PAAm凝胶的溶胀特性。溶胀机理分析表明, 凝胶的溶胀主要受聚合物网络内静电排斥作用和离子屏蔽效应控制。
关键词 高分子材料水凝胶pH敏感性丙烯酸丙烯酰胺溶胀    
Abstract:A series of pH sensitive poly(acrylic acid-co-acrylamide) hydrogels with different acrylic acid mass fraction (fAAc) were synthesized by the free radical polymerization. The swelling behavior of these hydrogels was studied in alkaline buffer solution and NaOH solution with different pH values, respectively. The results showed that the poly(acrylic acid) (PAAc) and poly(acrylic acid–co–acrylamide) (P(AAc–co–AAm)) hydrogels exhibit the excellent pH sensitivity and their equilibrium swelling ratios (ESR) in NaOH solution are higher than those in buffer solution, whereas the poly(acrylamide) (PAAm) only presents the pH sensitivity in NaOH solution. In the two kinds of solution, the ESR of P(AAc–co–AAm) hydrogels increased with the increasing of fAAc in polymer. Furthermore, in the buffer solution, the swelling behavior of P(AAc–co–AAm) hydrogel acts as similar as PAAc when the fAAc ≥20%, while it exhibits analogous swelling characteristics as PAAc and PAAm when the fAAc <20%. The swelling behaviors of hydrogels synthesized are mainly controlled by the electrostatic repulsive and the ion shielding effects in polymer network.
Key wordspolymer materials    hydrogel    pH sensitivity    acrylic acid    acryamide    swelling
收稿日期: 2011-04-26     
ZTFLH: 

O632

 
基金资助:

国家自然科学基金51071161资助项目。

1 YANG Huaiyu, ZHU Chengyun, WANG Li, Preparation and releasing mechanism of the environmental friend release microspheres, Materials Protection, 39(7S), 33(2006)

(杨怀玉, 朱澄云, 汪黎, 环境友好缓释微球的制备及释放机制, 材料保护, 39(7S), 33(2006))

2 A.K.Bajpai, Sandeep K., Shukla, Smitha Bhanu, Sanjana Kankane, Responsive polymers in controlled drug delivery, Progress in Polymer Science, 33, 1089(2008)

3 T.Tanaka, Collapse of gels and the critical endpoint, Physical Review Letters, 40,820(1978)

4 T.Tanaka, D.Fillmore, S.T.Sun, I.Nishio, G.Swislow, A.Shah, Phase transition in ionic gels, Physical Review Letters, 45,636(1980)

5 S.V.Vinogradov, T.K.Bronch, A.V.Kabanov, Nanosized cationic hydrogels for drug delivery preparation, properties and interactions with cells, Advanced Drug Delivery Reviews,54, 135(2002)

6 G.U.Ostrovidova, A.V.Makeev, M.M.Shamtsian, Polyfunctional film coatings for medical use, Material Science and Engineering:C, 23,545(2003)

7 S.Aluri, S.M.Janib, J.A.Mackay, Environmentally responsive peptides as anticancer drug carriers, Advanced Drug Delivery Reviews, 61, 940(2009)

8 E.Turan, T.Caykara, Swelling and network parameters of pH-sensitive poly (acrylamide-co-acrylic acid) hydrogels, Journal of Applied Polymer Science, 106, 2000(2007)

9 Y.X.Zhang, F.P.Wu, M.Z. Li, E.J. Wang, pH switching on-off semi-IPN hydrogel based on crosslinked poly(acrylamide–co–acrylic acid) and linear polyallyamine, Polymer, 46, 7695(2005)

10 D.Kim, K.Park, Swelling and mechanical properties of superporous hydrogels of poly (acrylamide-co-acrylic acid)/polyethylenimine interpenetrating polymer networks, Polymer, 45, 189(2004)

11 M.D.Kurkuri, T.M. Aminabhavi, Poly (vinyl alcohol) and poly (acrylic acid) sequential interpenetrating network pH-sensitive microspheres for the delivery of diclofenac sodium to the intestine, Journal of Controlled Release, 96, 10(2004)

12 ZHANG Xingying, CHENG Jue, ZHAO Jingbo, Polymer Chemistry (Beijing, Chemical Industry Press, 2006) p.226

(张兴英, 程珏, 赵京波,  高分子化学  (北京, 化学工业出版社, 2006) p.226)

13 LIU Canming, LI Huiyong, Inorganic and Analytical Chemistry (2) (Beijing, Science Press, 2009) p.92

(刘灿明, 李辉勇,  无机及分析化学 (2) (北京, 科学出版社, 2009) p.92)

14 JIA Zhenyu, Study on Modification of Superabsorbents Based on Acrylic Acid, PhD thesis, Northwestern Polytechnical University(2006)

(贾振宇, 丙烯酸高吸水树脂的高性能化研究, 博士学位论文, 西北工业大学(2006))

15 F.Llmain, T.Tanaka, E.Kokufuta, Volume transition in a gel driven by hydrogen bonding, Letters to Nature, 349, 400(1991)

16 S.Baek, A.R.Srinivasa, Modeling of the pH-sensitive behavior of an ionic gel in the presence of diffusion, Nonlinear Mechanics, 39, 1312(2004)
[1] 叶姣凤, 王飞, 左洋, 张钧翔, 罗晓晓, 冯利邦. 兼具高强度、高韧性和自修复性能的环氧树脂改性热可逆聚氨酯[J]. 材料研究学报, 2023, 37(4): 257-263.
[2] 李瀚楼, 焦晓光, 朱欢欢, 赵晓欢, 矫庆泽, 冯彩虹, 赵芸. 支链含氟聚酯的合成和性能[J]. 材料研究学报, 2023, 37(4): 315-320.
[3] 马逸舟, 赵秋莹, 杨路, 裘进浩. 热塑型聚酰亚胺/聚偏氟乙烯全有机复合薄膜的制备及其介电储能[J]. 材料研究学报, 2023, 37(2): 89-94.
[4] 杨琴, 王振, 房春娟, 王若迪, 高大航. 力学性能可控的CMC/AA/CB[8]/BET凝胶的制备及其吸附性[J]. 材料研究学报, 2022, 36(8): 628-634.
[5] 殷洁, 胡云涛, 刘慧, 杨逸霏, 王艺峰. 基于电沉积技术构建聚苯胺/海藻酸膜及电化学性能研究[J]. 材料研究学报, 2022, 36(4): 314-320.
[6] 申延龙, 李北罡. 磁性氨基酸功能化海藻酸铝凝胶聚合物的制备及对偶氮染料的超强吸附[J]. 材料研究学报, 2022, 36(3): 220-230.
[7] 廖静文, 饶春兴, 王艳芹, 陈维毅. 双网络Au NCs/HA/PVA复合水凝胶的荧光示踪性能和力学性能[J]. 材料研究学报, 2022, 36(2): 107-113.
[8] 龙庆, 王传洋. 不同碳黑含量PMMA的热降解行为和动力学分析[J]. 材料研究学报, 2022, 36(11): 837-844.
[9] 蒋平, 吴丽华, 吕太勇, José Pérez-Rigueiro, 王安萍. 蜘蛛大壶状腺丝的反复拉伸力学行为和性能[J]. 材料研究学报, 2022, 36(10): 747-759.
[10] 鄢俊, 杨进, 王涛, 徐桂龙, 李朝晖. 有机硅油改性水性酚醛的制备及其性能[J]. 材料研究学报, 2021, 35(9): 651-656.
[11] 张昊, 李帆, 常娜, 王海涛, 程博闻, 王攀磊. 羧酸型接枝淀粉吸附树脂的制备和对染料的去除性能[J]. 材料研究学报, 2021, 35(6): 419-432.
[12] 孙丽颖, 钱建华, 赵永芳. AgNWs-TPU/PVDF柔性薄膜电容传感器的制备和性能[J]. 材料研究学报, 2021, 35(6): 441-448.
[13] 唐开元, 黄洋, 黄湘舟, 葛颖, 李娉婷, 袁凡舒, 张威威, 孙东平. 碳化细菌纤维素的理化性质及其在甲醇电催化中的应用[J]. 材料研究学报, 2021, 35(4): 259-270.
[14] 苏晨文, 张婷玥, 郭丽伟, 李乐, 杨苹, 刘艳秋. 用于模拟细胞外基质的硫醇-烯水凝胶的制备[J]. 材料研究学报, 2021, 35(12): 903-910.
[15] 徐春萍, 陈春悦, 张永航, 龚维, 班大明. 含磷聚合物型阻燃剂(PMP)对乙烯基酯树脂(VER)的阻燃改性[J]. 材料研究学报, 2021, 35(11): 843-849.