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Research on the Preparation and Bioactivity of FHA Coatings |
ZHOU Hongming, ZENG Lin, YI Danqing, GUO Yanjun, LIU Furong |
School of Materials Science and engineering, Central South University, Changsha 410083 |
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Cite this article:
ZHOU Hongming ZENG Lin YI Danqing GUO Yanjun LIU Furong. Research on the Preparation and Bioactivity of FHA Coatings. Chin J Mater Res, 2010, 24(6): 643-648.
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Abstract FHA (Ca10(PO4)6(OH)F) powder of F doping Ca10(PO4)6OH)2 (HA) was synthesized by the precipitation method, and the FHA coating was prepared on the surface of the titanium alloy (Ti6Al4V) by electrophoretic deposition. XRD, SEM and EDS were used to investigate the influences of the substrate pretreatments on the coating morphology and binding force of the coatings, and the bioactivity of the coatings was also investigated. The results show that there are microcracks on the surface of the coatings pretreated by acid treatment, however, the microcracks are not found on the surface of the coatings treated by alkali treatment after acid treatment, having higher adhesion than those coatings pretreated by acid treatment. Bone-like calcium deficiency apatite, which grown like petal, with several hundred nanometers in length, formed on the surface of FHA coating after soaking, showing an excellent biological activity.
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Received: 22 July 2010
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Fund: Supported by the Major Project of International Cooperation of Hunan Province No. 2008WK2005, Special Finance Scheme of Post Doctoral Education of China No.200801350 and Research Fund for the Doctoral Program (for New Teacher) of Higher Education of China No.200805331062. |
[1] Rodriguez-Lorenzo L M, Hart J N, Gross K A. Influence of fluorine in the synthesis of apatites. Synthesis of solid solutions of hydroxy-fluorapatite [J]. Biomaterials, 2003, 24(21): 3777-3785.
[2] Suchanek W L, Shuk P, Byrappa K, et al. Mechanochemical-hydrothermal synthesis of carbonated apatite powders at room temperature [J]. Biomaterials, 2002, 23(3): 699-710.
[3] Tenhuisen K S, Martin R I, Klimkiewicz M, et al. Formation and properties of a synthetic bone composite: Hydroxyapatite- collagen [J]. Journal of Biomedical Materials Research, 1995, 29(7): 803-810.
[4] Locardi B, Pazzaglia U E, Gabbi C, et al. Thermal behaviour of hydroxyapatite intended for medical applications [J]. Biomaterials, 1993, 14(6): 437-441.
[5] Moreno E C, Kresak M, Kane J J, et al. ADSORPTION OF PROTEINS, PEPTIDES, AND ORGANIC ACIDS FROM BINARY MIXTURES ONTO HYDROXYLAPATITE.[J]. Langmuir, 1987, 3(4): 511-519.
[6] Chen Y, Miao X. Thermal and chemical stability of fluorohydroxyapatite ceramics with different fluorine contents [J]. Biomaterials,2005,26(11):1205-1210.
[7] Wei M, Evans J H. Synthesis and characterisation of hydroxyapatite and fluorapatite [C]. Palm Springs, CA, United states:Trans Tech Publications Ltd,2002.
[8] Lugscheider E, Knepper M, Heimberg B, et al. Cytotoxicity investigations of plasma sprayed calcium phosphate coatings [J]. Journal of Materials Science: Materials in Medicine, 1994, 5(6-7): 371-375.
[9] 陈晓明. 电泳共沉积—烧结法制备钛合金表面生物活性梯度陶瓷涂层的研究[D]. 武汉理工大学,2002.
[10] 姚亮. 纯钛基体表面电泳沉积羟基磷灰石涂层的研究[D]. 山东大学,2007.
[11] 曾麟, 周宏明, 易丹青, et al. FHA的热物性能及生物活性研究[J]. 功能材料, 2010, 41(1): 100-105.
[12] 段友容. 骨诱导Ca、P系陶瓷材料中类骨磷灰石层的形成、表征和体外动态研究模型的初步建立[D]. 四川大学, 2002.
[13] Hench L L, Wheeler D L, Greenspan D C. Molecular control of bioactivity in sol-gel glasses[J]. Journal of Sol-Gel Science and Technology, 1999, 13(1-3): 245-250.
[14] 林东洋. 磁控溅射技术制备HA/YSZ/Ti6A14V生物梯度复合材料[D]. 江苏大学,2006.
[15] 段友容, 吕万新, 王朝元, et al. 在动态模拟体液中致密CaP陶瓷表面形貌对类骨磷灰石层形成的影响研究[J]. 生物医学工程学杂志,2002,19(2):186-190.
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