|
|
|
| Glucose and Temperature Dual Stimuli Responsiveness of Intelligent Hollow Nanogels |
| WANG Congling1, XING Zhimin1, YAN Jie2, LI Lan2, ZHAO Huipeng2, ZHA Liusheng1,2 |
1.State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Donghua University, Shanghai 201620
2.Research Center for Analysis and Measurement, Donghua University, Shanghai 201620 |
|
Cite this article:
WANG Congling XING Zhimin YAN Jie LI Lan ZHAO Huipeng ZHA Liusheng. Glucose and Temperature Dual Stimuli Responsiveness of Intelligent Hollow Nanogels. Chin J Mater Res, 2012, 26(1): 44-48.
|
|
|
Abstract A novel type of intelligent hollow nanogels was prepared by two–step colloidal template polymerization, followed by introduction of phenylboronic acid groups and etching of the template, and was characterized by the Fourier transformation infrared spectroscopy, nuclear magnetic resonance, transmission electron microscopy and dynamic light scattering. The results show that the hollow nanogels are composed of poly(N–isopropylacrylamide) and poly(N–phenylboronic acid acrylamide), have interpenetrating polymer network structure and the morphological structure of inner cavity, and have both temperature and glucose stimuli responsive properties.
|
|
Received: 25 October 2011
|
|
|
| Fund: Supported by National Natural Science Foundation of China No.51073033. |
| 1 M.Motornov, Y.Roiter, I.Tokarev, S.Minko, Stimuli--responsive nanoparticles, nanogels and capsules for integrated multifunctional intelligent systems, Progress in Polymer Science (Oxford), 35(1--2), 174(2010)2 C.S.Peyratout, L.Dahne, Tailor--made polyelectrolyte microcapsules: From multilayers to smart containers, Angewandte Chemie--International Edition, 43(29), 3762(2004)3 M.H.Li, P.Keller, Stimuli--responsive polymer vesicles, Soft Matter, 5(5), 927(2009)4 Z.M.Xing, C.L.Wang, J.Yan, L.Zhang, L.Li, L.S.Zha, Dual stimuli responsive hollow nanogels with IPN structure for temperature controlling drug loading and pH triggering drug release, Soft Matter, 7(18), 7992(2011)5 J.Gu, F.Xia, Y.Wu, X.Qu, Z.Yang, L.Jiang, Programmable delivery of hydrophilic drug using dually responsive hydrogel cages, Journal of Controlled Release, 117(3), 396(2007)6 Z.M.Xing, C.L.Wang, J.Yan, L.Zhang, L.Li, L.S.Zha, pH/temperature dual stimuli--responsive microcapsules with interpenetrating polymer network structure, Colloid and Polymer Science, 288, 1723(2010) 7 L.S.Zha, Y.Zhang, W.L.Yang, S.K.Fu., Monodisperse temperature--sensitive microcontainers, Advanced Materials, 14(15), 1090(2002)8 Y.Maeda, H.Yamamoto, I.Ikeda, Effects of ionization on the phase behavior of poly(N--isopropylacrylamide--co--acrylic acid) and poly(N,N--diethylacrylamide--co--acrylic acid) in water, Colloid and Polymer Science, 282(11), 1268(2004)9 C.D.Jones, L.A.Lyon, Synthesis and characterization of multiresponsive core--shell microgels, Macromolecules, 33(22), 8301(2000)10 A.Matsumoto, R.Yoshida, K.Kataoka, Glucose--responsive polymer gel bearing phenylborate derivative as a glucose--sensing moiety operating at the physiological pH, Biomacromolecules, 5(3), 1038(2004)11 R.Pelton, Temperature--sensitive aqueous microgels, Advances in Colloid and Interface Science, 85, 1(2000) |
| No Suggested Reading articles found! |
|
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
Cited |
|
|
|
|
| |
Shared |
|
|
|
|
| |
Discussed |
|
|
|
|
