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| Effects of Cholesterol/Lecithin on the Microscopic Structure of Hydroxyapatite in Chitosan Substrate |
| DING Shan1,2, TANG Minjian1,2, ZHOU Changren1,2, TIAN Jinhuan1,2, LI Lihua1,2, |
1.Department of Materials Science and Engineering, Ji’nan University, Guangzhou 510630
2.Engineering Research Center of Artificial Organs and Materials, Ministry of Education, Jinan University, Guangzhou 510630 |
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Cite this article:
DING Shan TANG Minjian ZHOU Changren TIAN Jinhuan LI Lihua. Effects of Cholesterol/Lecithin on the Microscopic Structure of Hydroxyapatite in Chitosan Substrate. Chin J Mater Res, 2011, 25(4): 381-385.
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Abstract Chitosan/hydroxyapatite composite materials were prepared, the influence of synergistic action of cholesterol and lecithin on the microscopic structure of hydroxyapatite in the chitosan substrate was investigated. The results show: for the composite materials with different proportions of cholesterol and lecithin the microscopic structure of hydroxyapatite changed from the spherical to the claviform. When the proportion of lecithin and cholesterol is 5:1, the microscopic structure and size of hydroxyapatite in composite materials is closed to nature bone tissue. But in the control system without lecithin and cholesterol, the microscopic structures of hydroxyapatite are amorphous lamellate almostly. The cholesterol and lecithin can affect the microscopic structure of hydroxyapatite. Addition the difference proportions of lecithin and cholesterol in composite materials system were benefited of formation of hydroxyapatite production of differences microscopic structure.
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Received: 30 March 2011
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| Fund: Supported by National Science Foundation of China No.30900307 and Doctoral Fund of Ministry of Education of China No.200805590001. |
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