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| Evaluation of Biocompatibilities of Three Dental Alloys by Flow Cytometry |
| YU Tianhao1, 2, 3, 4 ZHANG Ning3, 5 ZHAN Desong1, 2, 3* |
1. Department of Cadres Clinic, School of Stomatology, China Medical University, Shenyang 110002
2. Department of Materials, School of Stomatology, China Medical University, Shenyang 110002
3. Liaoning Institute of Dental Research, Shenyang 110002
4. Central Laboratory, School of Stomatology, China Medical University, Shenyang 110002
5. Operating Room, School of Stomatology, China Medical University, Shenyang 110002 |
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Cite this article:
YU Tianhao, ZHANG Ning, ZHAN Desong,*. Evaluation of Biocompatibilities of Three Dental Alloys by Flow Cytometry. Chinese Journal of Materials Research, 2013, 27(6): 652-658.
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Abstract The L929 cells of mouse were treated in vitro with leaching liquids of 3 dental alloys (a gold alloy, a cobalt-chromium alloy and a nickel-chromium alloy) .The effects of the leaching liquids on proliferation and apoptosis of L929 cells were examined by flow cytometry to evaluate the biocompatibilities of 3 dental alloys. Results show that the gold alloy has little effect on the proliferation and apoptosis of the cells, with less cytotoxicity, demonstrated its biocompatibility is excellent; the nickel-chromium alloy has greater impact on the proliferation and is likely to induce apoptosis, with great cytotoxicity and poor biocompatibility; and the performance of the cobalt-chromium alloy is in the middle of above two alloys, and its biocompatibility is good as well.
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