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Chin J Mater Res  2008, Vol. 22 Issue (5): 495-499    DOI:
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The preparation and blood compatibility of pure iron thin film using filter cathode vacuum arc
Sheng-Fa ZHU;;;;;
西南交通大学材料先进技术教育部重点实验室;中国工程物理研究院
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Sheng-Fa ZHU. The preparation and blood compatibility of pure iron thin film using filter cathode vacuum arc. Chin J Mater Res, 2008, 22(5): 495-499.

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Abstract  Iron thin film were deposited on silicon substrate using filter cathode vacuum arc. Composition and valence studies were carried out by X-ray photoelectron spectroscopy (XPS); Glancing angle X-ray diffraction (GAXRD) was employed to examine the phase structure. In vitro blood compatibility tests, including platelet adherent, prothrombin time(PT) and thrombin time(TT), were used to evaluate the antithrombogenic properties. Scanning electron microscopy (SEM) and optical microscopy were employed to evaluate the surface morphology of the blood platelets on the films. The results have shown that the number of adherent platelets, the aggregation and pseudopodium were reduced compared to that observed on the 316L stainless steel. The PT and TT for iron thin films are almost the same as for the original plasma, which indicates that the tendency for activating blood coagulation factors is very slight.
Key words:  Filter cathode vacuum arc      iron thin film      blood compatibility      
Received:  16 October 2007     
ZTFLH:  TB43.R318  

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https://www.cjmr.org/EN/     OR     https://www.cjmr.org/EN/Y2008/V22/I5/495

1 U.Sigwart,J.Puel,V.Mirkovitch,F.Joffre, L.Kappenberger,Intracoronary stents to prevent oc- clusion and restenosis after transluminal angioplasty,The New England Journal of Medicine,316,701(1987)
2 C.D.Mario,H.Griffiths,O.Goktekin,N.Peeters,J.Verbist, M.Bosiers,K.Deloose,B.Heublein,R.Rohde,V.Kasese, C.Ilsley,R.Erbel,Drug-eluting bioabsorbable magnesium stent,J.Interv.Cardio,17(6),391(2004)
3 B.Heublein,R.Rohde,V.Kaese,M.Niemeyer,W.Hartung, A.Haverich,Biocorrosion of magnesium alloys:a new principle in cardiovascular implant technology? Heart,89, 651(2003)
4 R.Waksman,Metallic bioabsorbable stents:concepts,ex- perimental findings,early clinical results and the future, ACC Current Journal Review,14(10),36(2005)
5 G.Mani,M.D.Feldman,Coronary stents:A materials per- spective,Biomaterials,28,1689(2007)
6 M.Peuster,P.Wohlsein,M.Brügmann,M.Ehlerding, K.Seidler,C.Fink,H.Brauer,A.Fischer,G.Hausdorf,A novel approach to temporary stenting:degradable car- diovascular stents produced from corrodible metal-results 6-18 months after implantation into New Zealand white rabbits,Heart,86(5),563(2001)
7 M.Peuster,C.Hesse,T.Schloo,T.Schloo,C.Fink, P.Beerbaum,C.von Schnakenburg,Long-term biocompat- ibility of a corrodible peripheral iron stent in the porcine descending aorta,Biomaterials,27,4955(2006)
8 P.P.Mueller,T.Maya,A.Perz,H.Hauser,M.Peuster,Con- trol of smooth muscle cell proliferation by ferrous iron. Biomaterials,27(10),2193(2006)
9 N.Huang,P.Yang,Y.X.Leng,J.Y.Chen,H.Sun,J.Wang, G.J.Wang,P.D.Ding,T.F.Xi,Y.Leng,Hemocompatibility of titanium oxide films,Biomaterials,24,2177(2003)
10 N.Huang,P.Yang,Y.X.Leng,J.Wang,H.Sun,J.Y.Chen, G.J.Wan,Surface modification of biomaterials by plasma immersion ion implantation,Surf.Coat.Technol.,186, 218(2004)
11 M.I.Jones,I.R.McColl,D.M.Grant,K.G.Parker, T.L.Parker,Protein adsorption and platelet attach- ment and activation,on TiN,TiC,and DLC coatings on titanium for cardiovascular applications,J.Biomed Mater.Res.,52,413(2000)
12 Y.X.Leng,H.Sun,P.Yang,J.Y.Chen,J.Wang,G.J.Wan, N.Huang,X.B.Tian,Biomedical properties of tantalum ni- tride films synthesized by reactive magnetron sputtering, Thin Solid Films,398/399,471(2001)
13 F.Z.Cui,D.J.Li,A review of investigations on biocompat- ibility of diamond-like carbon and carbon nitride films, Surf.Coat.Technol.,131,481(2000)
14 ZHANG Xiyan,LI Cong,SHI Minghua,LIU Nianfu,QIU Shaoyu,ZHANG Qiang,The relation between grain size and the corrosion resistance of nanocrystalline zircaloy-4, Rare Metal Materials and Engineering,37(2),273(2008) (张喜燕,李聪,石明华,刘年富,邱绍宇,张强,纳米结构锆-4合金腐蚀速率与晶粒尺寸的关系,稀有金属材料与工程,37(2),273(2008))
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