材料研究学报  2013, Vol. 27 Issue (6): 652-658

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使用流式细胞仪评价3种牙科合金材料的生物相容性

毓天昊1, 2, 3, 4 张 宁3, 5 战德松1, 2, 3

1. 中国医科大学口腔医学院干诊科 沈阳 110002 2. 中国医科大学口腔医学院材料教研室 沈阳 110002 3. 辽宁省口腔医学研究所 沈阳 110002 4. 中国医科大学口腔医学院中心实验室 沈阳 110002 5. 中国医科大学口腔医学院手术室 沈阳 110002

Evaluation of Biocompatibilities of Three Dental Alloys by Flow Cytometry

YU Tianhao1, 2, 3, 4 ZHANG Ning3, 5 ZHAN Desong1, 2, 3*

1. Department of Cadres Clinic, School of Stomatology, China Medical University, Shenyang 110002 2. Department of Materials, School of Stomatology, China Medical University, Shenyang 110002 3. Liaoning Institute of Dental Research, Shenyang 110002 4. Central Laboratory, School of Stomatology, China Medical University, Shenyang 110002 5. Operating Room, School of Stomatology, China Medical University, Shenyang 110002

毓天昊,张宁,战德松. 使用流式细胞仪评价3种牙科合金材料的生物相容性[J]. 材料研究学报, 2013, 27(6): 652-658.
. Evaluation of Biocompatibilities of Three Dental Alloys by Flow Cytometry[J]. Chinese Journal of Materials Research, 2013, 27(6): 652-658.

摘要 相关文章 Metrics 全文: PDF(1941 KB)   摘要: 采用金合金、钴铬合金、镍铬合金等三种牙科合金浸提液与L929细胞联合培养, 使用流式细胞仪检测浸提液对细胞的增殖与凋亡的影响, 比较三种合金的生物相容性。结果表明: 金合金对细胞增殖的影响很小, 不易引起细胞凋亡, 细胞毒性小, 表明其生物相容性优良; 镍铬合金对细胞增殖的影响较大, 易引起细胞凋亡, 细胞毒性较大, 表明其生物相容性差; 钴铬合金的情况介于二者之间, 也具有较好的生物相容性。 Abstract： The L929 cells of mouse were treated in vitro with leaching liquids of 3 dental alloys (a gold alloy, a cobalt-chromium alloy and a nickel-chromium alloy) .The effects of the leaching liquids on proliferation and apoptosis of L929 cells were examined by flow cytometry to evaluate the biocompatibilities of 3 dental alloys. Results show that the gold alloy has little effect on the proliferation and apoptosis of the cells, with less cytotoxicity, demonstrated its biocompatibility is excellent; the nickel-chromium alloy has greater impact on the proliferation and is likely to induce apoptosis, with great cytotoxicity and poor biocompatibility; and the performance of the cobalt-chromium alloy is in the middle of above two alloys, and its biocompatibility is good as well.      ZTFLH:  分类号 R318   服务 把本文推荐给朋友 加入引用管理器 E-mail Alert RSS 作者相关文章 44.8K 链接本文: https://www.cjmr.org/CN/      或      https://www.cjmr.org/CN/Y2013/V27/I6/652 No related articles found! Viewed Full text Abstract Cited   Shared      Discussed